RNA-seq of TM3 Leydig and TM4 Sertoli cells under MEHP exposure
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × TM3_DMSO vs 3 × TM3_MEHP vs 3 × TM4_DMSO vs 3 × TM4_MEHPGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE243503_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1018824 and SRA study SRP461613. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7789657 TM3_DMSO_rep1 TM3_DMSO
- GSM7789658 TM3_DMSO_rep2 TM3_DMSO
- GSM7789659 TM3_DMSO_rep3 TM3_DMSO
- GSM7789660 TM3_MEHP_rep1 TM3_MEHP
- GSM7789661 TM3_MEHP_rep2 TM3_MEHP
- GSM7789662 TM3_MEHP_rep3 TM3_MEHP
- GSM7789663 TM4_DMSO_rep1 TM4_DMSO
- GSM7789664 TM4_DMSO_rep2 TM4_DMSO
- GSM7789665 TM4_DMSO_rep3 TM4_DMSO
- GSM7789666 TM4_MEHP_rep1 TM4_MEHP
- GSM7789667 TM4_MEHP_rep2 TM4_MEHP
- GSM7789668 TM4_MEHP_rep3 TM4_MEHP
- GSE330728 Single-nucleus RNA-seq atlas of 17 ASD-risk mouse lines under early-postnatal fluoxetine or lithium exposure (4-plex On-Chip Multiplexed) 53 samples shares exposure, rna-seq
- GSE325692 Multi-omic analysis reveals brain-blood concordance and persistent neuroimmune reprogramming with stress and toxicant exposure in a mouse model of Gulf War Illness [RNA-Seq] 30 samples shares exposure, rna-seq
- GSE244385 Short-term cold exposure induces persistent epigenomic memory in brown fat [RNA-Seq] 24 samples shares exposure, rna-seq
- GSE285128 Developmental exposure to air pollution particulates increases asthma severity, alters the RNA transcriptome, and DNA methylation in female adult progeny [RNA-Seq] 23 samples shares exposure, rna-seq
- GSE197871 RNA-seq analysis of differentiated noradrenergic neurons (1C11NE) and microglia (BV2) following exposure to acrylamide (ACR) 21 samples shares exposure, rna-seq
- GSE226609 Mouse lung tissue RNA-Seq from C57Bl6 wild type and ALOX15 KO mice with and without house dust mite (HDM) exposure. 20 samples shares exposure, rna-seq
- GSE322523 Mouse heart RNA-seq in isoproterenol (ISO) injury model with or without polystyrene nanoplastics co-exposure 18 samples shares exposure, rna-seq
- GSE280174 Impact of Early Bisphenol A Exposure on Transcriptome and Chromatin Accessibility in Brain Oligodendrocytes of Juvenile Mice [RNA-seq] 16 samples shares exposure, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.