TAF1 is required for fetal but not adult hematopoiesis in mice
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 60 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 60 samples: 16 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- TAF1 is required for fetal but not adult hematopoiesis in miceDevelopmental cell · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE248657_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1045521 and SRA study SRP474331. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 46 samples.
How we read this: 16 replicated groups read from 60 sample titles; they account for 46 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7918354 Control_1 Control
- GSM7918355 Control_2 Control
- GSM7918356 Control_3 Control
- GSM7918357 TAF1_KO_1 TAF1_KO
- GSM7918358 TAF1_KO_2 TAF1_KO
- GSM7918359 Control-1 TAF1
- GSM7918360 Control-2 TAF1
- GSM7918361 KO-1 TAF1
- GSM7918362 KO-2 TAF1
- GSM7918363 Control PoII
- GSM7918364 KO PoII
- GSM7918365 Control Input
- GSM7918366 KO Input
- GSM7918387 Control_Day0_1 Control_Day0
- GSM7918388 Control_Day0_2 Control_Day0
- GSM7918389 Control_Day0_3 Control_Day0
- GSM7918390 TAF1_KO_Day0_1 TAF1_KO_Day0
- GSM7918391 TAF1_KO_Day0_2 TAF1_KO_Day0
- GSM7918392 TAF1_KO_Day0_3 TAF1_KO_Day0
- GSM7918393 Control_Day3_1 Control_Day3
- GSM7918394 Control_Day3_2 Control_Day3
- GSM7918395 Control_Day3_3 Control_Day3
- GSM7918396 TAF1_KO_Day3_1 TAF1_KO_Day3
- GSM7918397 TAF1_KO_Day3_2 TAF1_KO_Day3
- GSM7918398 TAF1_KO_Day3_3 TAF1_KO_Day3
- GSM7918399 Control_Day5_Macrophage_1 Control_Day5_Macrophage
- GSM7918400 Control_Day5_Macrophage_2 Control_Day5_Macrophage
- GSM7918401 Control_Day5_Macrophage_3 Control_Day5_Macrophage
- GSM7918402 Control_Day5_Granulocyte_1 Control_Day5_Granulocyte
- GSM7918403 Control_Day5_Granulocyte_2 Control_Day5_Granulocyte
- GSM7918404 Control_Day5_Granulocyte_3 Control_Day5_Granulocyte
- GSM7918405 TAF1_KO_Day5_Macrophage_1 TAF1_KO_Day5_Macrophage
- GSM7918406 TAF1_KO_Day5_Macrophage_2 TAF1_KO_Day5_Macrophage
- GSM7918407 TAF1_KO_Day5_Macrophage_3 TAF1_KO_Day5_Macrophage
- GSM7918408 TAF1_KO_Day5_Granulocyte_1 TAF1_KO_Day5_Granulocyte
- GSM7918409 TAF1_KO_Day5_Granulocyte_2 TAF1_KO_Day5_Granulocyte
- GSM7918410 TAF1_KO_Day5_Granulocyte_3 TAF1_KO_Day5_Granulocyte
- GSM7918411 Control_Day7_Macrophage_1 Control_Day7_Macrophage
- GSM7918412 Control_Day7_Macrophage_2 Control_Day7_Macrophage
- GSM7918413 Control_Day7_Macrophage_3 Control_Day7_Macrophage
+ 20 more — browse all 60 samples with per-sample file links →
- GSE229427 Tracking spatio-temporal dynamics of the endothelial niche during fetal hematopoiesis 216 samples shares hematopoiesis, fetal
- GSE315987 M-cadherin regulates the formation of adherens junctions and secondary myofibers during fetal myogenesis to determine adult myofiber number and muscle mass 88 samples shares fetal, adult
- GSE214528 Histone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis 32 samples shares fetal, adult
- GSE214527 Histone chaperon ASF1B recruits distinct epigenetic factors in regulation of histone variant H3.3 during the fetal and adult erythropoiesis [ChIP-seq] 28 samples shares fetal, adult
- GSE320330 Fetal growth restriction leads to prolonged nephrogenesis and persistent developmental gene dysregulation in the adult kidney 18 samples shares fetal, adult
- GSE269184 Dynamic expression of Erg controls fetal-to-adult maturation of the hematopoietic system [RNA-seq] 12 samples shares fetal, adult
- GSE204933 Age-associated chromatin reorganization drives overexpression of a novel Btaf1 variant regulating HSC self-renewal and MkP differentiation in male mice 82 samples shares taf1
- GSE291544 Roles of chromosomal and gonadal sex in the fetal and placental responses to maternal food restriction in mice [junctional zone/decidua] 60 samples shares fetal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.