Gene expression profiling of CTCL patient-derived cell lines after GTSF1 knockdown
RNA-seq (gene expression) · human · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Memory T-Cell Phenotype in Cutaneous T-Cell Lymphoma Is Modified by Germline Gene Gametocyte Specific Factor 1Experimental dermatology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE270818_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1128569 and SRA study SRP516230. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 6 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8352619 Mac2A, SCR, 1 Mac2A, SCR,
- GSM8352620 Mac2A, SCR, 2 Mac2A, SCR,
- GSM8352621 Mac2A, SCR, 3 Mac2A, SCR,
- GSM8352622 Mac2A, shGTSF1, 1 Mac2A, shGTSF1,
- GSM8352623 Mac2A, shGTSF1, 2 Mac2A, shGTSF1,
- GSM8352624 Mac2A, shGTSF1, 3 Mac2A, shGTSF1,
- GSM8352625 MyLa, SCR, 1 MyLa, SCR,
- GSM8352626 MyLa, SCR, 2 MyLa, SCR,
- GSM8352627 MyLa, SCR, 3 MyLa, SCR,
- GSM8352628 MyLa, shGTSF1, 1 MyLa, shGTSF1,
- GSM8352629 MyLa, shGTSF1, 2 MyLa, shGTSF1,
- GSM8352630 MyLa, shGTSF1, 3 MyLa, shGTSF1,
- GSM8352631 SZ4, SCR, 1 SZ4, SCR,
- GSM8352632 SZ4, SCR, 2 SZ4, SCR,
- GSM8352633 SZ4, SCR, 3 SZ4, SCR,
- GSM8352634 SZ4, shGTSF1, 1 SZ4, shGTSF1,
- GSM8352635 SZ4, shGTSF1, 2 SZ4, shGTSF1,
- GSM8352636 SZ4, shGTSF1, 3 SZ4, shGTSF1,
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.