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Hepatic Metabolic Adaption During Prolonged Cyclic Calorie Restriction

GSE289993 Mus musculus Expression profiling by high throughput sequencing 10 samples 2025/12/31 GPL28457
Summary
The liver plays a crucial role in metabolic processes, and its response to fasting or intermittent fasting has been extensively studied. However, the effects of non-fasting calorie restriction (CR) on hepatic changes remain underexplored. The current data revealed new hepatic metabolic changes that do not follow traditional fasting patterns, demonstrating the liver's high metabolic adaptability to dietary content and eating habit changes.
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