RNA sequencing analysis of kidney tissues in MRL/lpr lupus-prone mice and C57BL/6 controls
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × C57BL/6_8W vs 3 × C57BL/6_17W vs 3 × MRL/lpr_8W vs 3 × MRL/lpr_17WGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- miR-7213-5p-mediated suppression of CCL19 in fibroblast cells may attenuate lupus nephritisClinical and experimental medicine · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE296205_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1258206 and SRA study SRP582797. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8967035 C57BL/6_8W_1 C57BL/6_8W
- GSM8967036 C57BL/6_8W_2 C57BL/6_8W
- GSM8967037 C57BL/6_8W_3 C57BL/6_8W
- GSM8967038 C57BL/6_17W_1 C57BL/6_17W
- GSM8967039 C57BL/6_17W_2 C57BL/6_17W
- GSM8967040 C57BL/6_17W_3 C57BL/6_17W
- GSM8967041 MRL/lpr_8W_1 MRL/lpr_8W
- GSM8967042 MRL/lpr_8W_2 MRL/lpr_8W
- GSM8967043 MRL/lpr_8W_3 MRL/lpr_8W
- GSM8967044 MRL/lpr_17W_1 MRL/lpr_17W
- GSM8967045 MRL/lpr_17W_2 MRL/lpr_17W
- GSM8967046 MRL/lpr_17W_3 MRL/lpr_17W
- GSE305103 RNA-seq of liver, kidney, and quadriceps muscle from corylin-treated and control C57BL/6J mice 54 samples shares c57bl, kidney
- GSE228455 Gene expression profile at single cell level of monocytes sorted from C57BL/6J mouse ear tissue at 3 weeks post Leishmania major infection [scRNA-seq] 218 samples shares c57bl
- GSE302019 Bulk RNA sequencing to investigate transcriptional profiles of lung macrophage subpopulations isolated from wild-type C57BL/6J and Spp1-EGFP knock-in reporter mice subjected to intratracheal administration of bleomycin or PBS. 24 samples shares c57bl
- GSE301801 Bulk RNA-seq analysis of WT C57BL/6 mise treated with Control, Choleste-help normal lot, toxic lot, and Puberulic acid 20 samples shares c57bl
- GSE246154 Single-nucleus RNA-sequencing (snRNA-Seq) of brain cells from tumor-bearing C57BL/6 mice 19 samples shares c57bl
- GSE228456 Cell-intrinsic effect of IL-7R signaling of monocytes within C57BL/6J mouse ears infected with Leishmania major [bulk RNA-seq] 87 samples shares c57bl
- GSE263132 Naïve CD8 T cell RNA sequencing in C57BL/6 and MD4 mice 10 samples shares c57bl
- GSE274825 RNA sequencing of MC38 tumor cells from control-diet- and high-fat-diet-fed C57BL/6J mice 10 samples shares c57bl
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.