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Transcriptomic profiling of C2C12 myotubes treated with D-galactose and red ginseng-derived interventions

GSE333910 Mus musculus Expression profiling by high throughput sequencing 30 samples 2026/06/06 GPL28457
Summary
This study investigated transcriptomic alterations in differentiated C2C12 myotubes following treatment with D-galactose and red ginseng-derived interventions. Fully differentiated C2C12 myotubes were treated with Korean Red Ginseng water extract (RGW), saponin fraction (SFr), non-saponin fraction (NSFr), or ginsenoside Rb2 either alone or in combination with D-galactose. Bulk RNA sequencing was performed to characterize the transcriptional effects of each intervention under basal conditions and to evaluate their modulatory effects on D-galactose-induced cellular aging-associated transcriptomic changes.
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