Drug, across the briefings
Avelumab across 16 cancers
Avelumab appears in 16 of the briefings; its FDA label names 3 of those diseases.
| Disease | FDA label | Open Targets stage, on which gene | Trials | Active |
|---|---|---|---|---|
| Bladder cancer | label names disease | approved on CD274 | 32 | 12 |
| Kidney cancer | label names disease | approved on CD274 | 23 | 6 |
| Merkel cell carcinoma | label names disease | approved on CD274 | 22 | 8 |
| Anal cancer | approved on CD274 | 3 | 1 | |
| Cervical cancer | approved on CD274 | 8 | 3 | |
| Cholangiocarcinoma | approved on CD274 | 1 | 1 | |
| Cutaneous squamous cell carcinoma | approved on CD274 | 4 | 3 | |
| Esophageal cancer | approved on CD274 | 6 | 1 | |
| Gastric cancer | approved on CD274 | 14 | 3 | |
| Head and neck cancer | approved on CD274 | 21 | 7 | |
| Hodgkin lymphoma | approved on CD274 | 2 | 0 | |
| Lung cancer | approved on CD274 | 36 | 4 | |
| Mesothelioma | approved on CD274 | 4 | 1 | |
| Nasopharyngeal carcinoma | approved on CD274 | 2 | 0 | |
| Small cell lung cancer | approved on CD274 | 13 | 2 | |
| Vulvar cancer | approved on CD274 | 1 | 1 |
The label column is the briefing's openFDA stage: a label whose Indications and Usage names the disease. The Open Targets column is the furthest clinical stage recorded for the drug against any gene on that briefing's target list, in any indication. Trials are ClinicalTrials.gov interventional studies naming the drug and the disease, from the briefing's trials stage; a dash means the briefing did not search this drug in that disease (it searches the drugs Open Targets lists against its own genes), which is not the same as none. Salt forms, biosimilar suffixes and formulation words are merged by the same rule the briefings use.