CDK4 overexpression is a predictive biomarker for resistance to conventional chemotherapy in osteosarcoma patients
human · 50 samples
- Organism
- Homo sapiens (human)
- Topic
- OsteosarcomaThis series is part of our curated briefing on it.
- Samples
- 50 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE154540_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
Also filed as BioProject PRJNA646638. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 50 more — browse all 50 samples with per-sample file links →
- GSE21257 Genome-wide gene expression profiling on pre-chemotherapy biopsies of osteosarcoma patients who developed metastases within 5yrs (n=34) and patients who did not develop metastases within 5yrs (n=19) 53 samples same disease briefing · shares chemotherapy, osteosarcoma
- GSE268415 PRKDC Induces Chemoresistance in Osteosarcoma by Recruiting GDE2 to Stabilize GNAS and Activate AKT 12 samples same disease briefing · shares osteosarcoma, resistance
- GSE218037 Transcriptome sequencing reveals expression characteristics of osteosarcoma before and after neoadjuvant chemotherapy 10 samples same disease briefing · shares chemotherapy, osteosarcoma
- GSE317900 ZDHHC8-mediated β-catenin palmitoylation promotes WNT signaling activation and drives cisplatin resistance in osteosarcoma 8 samples same disease briefing · shares osteosarcoma, resistance
- GSE234632 Augmented Drug Resistance of Osteosarcoma Cells within Decalcified Bone Matrix Scaffold: the role of Glutamine Metabolism 6 samples same disease briefing · shares osteosarcoma, resistance
- GSE270506 Epigenetic heterogeneity and state-specific transcriptional programs determine differential drug response in osteosarcoma. 279 samples same disease briefing · shares osteosarcoma
- GSE42352 Genome-wide gene expression profiling of mesenchymal stem cells, osteosarcoma cells, and osteosarcoma cell lines. 118 samples same disease briefing · shares osteosarcoma
- GSE259286 In vitro modeling of nutritional and mitochondrial-targeted therapies for osteosarcoma 98 samples same disease briefing · shares osteosarcoma
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.